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1

Design, synthesis and biological evaluation of imidazopyridine/pyrimidine-chalcone derivatives as potential anticancer agents

Kamal, Ahmed, Reddy, J. Surendranadha, Ramaiah, M. Janaki, Dastagiri, D., Bharathi, E. Vijaya, Prem Sagar, M. Victor, Pushpavalli, S. N. C. V. L., Ray, Paramita, Pal-Bhadra, Manika

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 330 KB

english, 2010

2

Synthesis of Imidazothiazole–Chalcone Derivatives as Anticancer and Apoptosis Inducing Agents

Dr. Ahmed Kamal, D. Dastagiri, Dr. M. Janaki Ramaiah, J. Surendranadha Reddy, E. Vijaya Bharathi, Chatla Srinivas, S. N. C. V. L. Pushpavalli, Dhananjaya Pal, Dr. Manika Pal-Bhadra

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 410 KB

english, 2010

3

Synthesis and anti-cancer activity of chalcone linked imidazolones

Ahmed Kamal, G. Ramakrishna, P. Raju, A. Viswanath, M. Janaki Ramaiah, G. Balakishan, Manika Pal-Bhadra

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2010

Langue:

english

Fichier:

PDF, 584 KB

english, 2010

4

Design, synthesis and biological evaluation of 3,5-diaryl-isoxazoline/isoxazole-pyrrolobenzodiazepine conjugates as potential anticancer agents

Ahmed Kamal, J. Surendranadha Reddy, M. Janaki Ramaiah, D. Dastagiri, E. Vijaya Bharathi, M. Ameruddin Azhar, Farheen Sultana, S.N.C.V.L. Pushpavalli, Manika Pal-Bhadra, Aarti Juvekar, Subrata Sen, Su

Journal:

European Journal of Medicinal Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 738 KB

english, 2010

5

Synthesis and biological evaluation of novel Mannich bases of 2-arylimidazo[2,1-b]benzothiazoles as potential anti-cancer agents

Ravindra M. Kumbhare, K. Vijay Kumar, M. Janaki Ramaiah, Tulshiram Dadmal, S.N.C.V.L. Pushpavalli, Debasmita Mukhopadhyay, B. Divya, T. Anjana Devi, Umesh Kosurkar, Manika Pal-Bhadra

Journal:

European Journal of Medicinal Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 978 KB

english, 2011

6

3-Diarylethyne quinazolinones: a new class of senescence inducers

Kamal, Ahmed, Sultana, Farheen, Ramaiah, M. Janaki, Srikanth, Y. V. V., Viswanath, A., Bharathi, E. Vijaya, Nayak, Ranjita, Pushpavalli, S. N. C. V. L., Srinivas, Chatla, Pal-Bhadra, Manika

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 726 KB

english, 2013

7

Design, synthesis, in silico pharmacokinetics prediction and biological evaluation of 1,4-dihydroindeno[1,2-c]pyrazole chalcone as EGFR /Akt pathway inhibitors

Khan, Irfan, Garikapati, Koteswara Rao, Setti, Aravind, Shaik, Anver Basha, Kanth Makani, Venkatesh Krishna, Shareef, Mohd Adil, Rajpurohit, Hemshikha, Vangara, Namratha, Pal-Bhadra, Manika, Kamal, Ah

Journal:

European Journal of Medicinal Chemistry

Année:

2018

Langue:

english

Fichier:

PDF, 2.05 MB

english, 2018

8

ChemInform Abstract: Synthesis and Biological Evaluation of Novel Mannich Bases of 2-Arylimidazo[2,1-b]benzothiazoles as Potential Anticancer Agents.

Ravindra M. Kumbhare, K. Vijay Kumar, M. Janaki Ramaiah, Tulshiram Dadmal, S. N. C. V. L. Pushpavalli, Debasmita Mukhopadhyay, B. Divya, T. Anjana Devi, Umesh Kosurkar, Manika Pal-Bhadra

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 37 KB

english, 2012

9

ChemInform Abstract: Synthesis and Anticancer Activity of Chalcone-Pyrrolobenzodiazepine Conjugates Linked via 1,2,3-Triazole Ring Side-Armed with Alkane Spacers.

Ahmed Kamal, S. Prabhakar, M. Janaki Ramaiah, P. Venkat Reddy, Ch. Ratna Reddy, A. Mallareddy, Nagula Shankaraiah, T. Lakshmi Narayan Reddy, S. N. C. V. L. Pushpavalli, Manika Pal-Bhadra

Journal:

Année:

2012

Fichier:

PDF, 28 KB

2012

10

Development of Pyrrolo[2,1-c][1,4]benzodiazepine β-Galactoside Prodrugs for Selective Therapy of Cancer by ADEPT and PMT

Ahmed Kamal, Venkatesh Tekumalla, Anita Krishnan, Manika Pal-Bhadra, Utpal Bhadra

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 894 KB

english, 2008

11

Synthesis, anticancer activity and apoptosis inducing ability of anthranilamide-PBD conjugates

Ahmed Kamal, E. Vijaya Bharathi, M. Janaki Ramaiah, J. Surendranadha Reddy, D. Dastagiri, A. Viswanath, Farheen Sultana, S.N.C.V.L. Pushpavalli, Manika Pal-Bhadra, Aarti Juvekar, Subrata Sen, Surekha

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2010

Langue:

english

Fichier:

PDF, 435 KB

english, 2010

12

Quinazolinone linked pyrrolo[2,1-c][1,4]benzodiazepine (PBD) conjugates: Design, synthesis and biological evaluation as potential anticancer agents

Ahmed Kamal, E. Vijaya Bharathi, M. Janaki Ramaiah, D. Dastagiri, J. Surendranadha Reddy, A. Viswanath, Farheen Sultana, S.N.C.V.L. Pushpavalli, Manika Pal-Bhadra, Hemant Kumar Srivastava, G. Narahari

Journal:

Bioorganic & Medicinal Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 805 KB

english, 2010

13

Synthesis, DNA-binding ability and anticancer activity of benzothiazole/benzoxazole–pyrrolo[2,1-c][1,4]benzodiazepine conjugates

Ahmed Kamal, K. Srinivasa Reddy, M. Naseer A. Khan, Rajesh V.C.R.N.C. Shetti, M. Janaki Ramaiah, S.N.C.V.L. Pushpavalli, Chatla Srinivas, Manika Pal-Bhadra, Mukesh Chourasia, G. Narahari Sastry, Aarti

Journal:

Bioorganic & Medicinal Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 1.33 MB

english, 2010

14

Synthesis, anticancer activity and mitochondrial mediated apoptosis inducing ability of 2,5-diaryloxadiazole–pyrrolobenzodiazepine conjugates

Ahmed Kamal, D. Dastagiri, M. Janaki Ramaiah, E. Vijaya Bharathi, J. Surendranadha Reddy, G. Balakishan, Pranjal Sarma, S.N.C.V.L. Pushpavalli, Manika Pal-Bhadra, Aarti Juvekar, Subrata Sen, Surekha Z

Journal:

Bioorganic & Medicinal Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 693 KB

english, 2010

15

Synthesis and biological evaluation of estradiol linked pyrrolo[2,1-c][1,4]benzodiazepine (PBD) conjugates as potential anticancer agents

Ahmed Kamal, M. Kashi Reddy, M. Janaki Ramaiah, Rajender, J. Surendranadha Reddy, Y.V.V. Srikanth, D. Dastagiri, E. Vijaya Bharathi, S.N.C.V.L. Pushpavalli, Pranjal Sarma, Manika Pal-Bhadra

Journal:

Bioorganic & Medicinal Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 1.52 MB

english, 2011

16

Synthesis and biological evaluation of 4β-acrylamidopodophyllotoxin congeners as DNA damaging agents

Ahmed Kamal, Paidakula Suresh, M. Janaki Ramaiah, Adla Mallareddy, Banala Ashwini Kumar, Paidakula Raju, J. Vinay Gopal, S.N.C.V.L. Pushpavalli, A. Lavanya, Pranjal Sarma, Manika Pal-Bhadra

Journal:

Bioorganic & Medicinal Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 1.25 MB

english, 2011

17

Synthesis and biological evaluation of anilino substituted pyrimidine linked pyrrolobenzodiazepines as potential anticancer agents

Ahmed Kamal, J. Surendranadha Reddy, M. Janaki Ramaiah, E. Vijaya Bharathi, D. Dastagiri, M. Kashi Reddy, S.N.C.V.L. Pushpavalli, Manika Pal-Bhadra

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2010

Langue:

english

Fichier:

PDF, 407 KB

english, 2010

18

10.1038/5926

Birchler, James A, Pal-Bhadra, Manika, Bhadra, Utpal

Journal:

Nature Genetics

Année:

1999

Langue:

english

Fichier:

PDF, 131 KB

english, 1999

19

Dosage Dependent Gene Regulation and the Compensation of the X Chromosome inDrosophilaMales

James A. Birchler, Manika Pal-Bhadra, Utpal Bhadra

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 407 KB

english, 2003

20

Anthranilamide–Pyrazolo[1,5-a]pyrimidine Conjugates as p53 Activators in Cervical Cancer Cells

Dr. Ahmed Kamal, Jaki R. Tamboli, Dr. M. Janaki Ramaiah, Dr. S. F. Adil, G. Koteswara Rao, A. Viswanath, Adla Mallareddy, Dr. S. N. C. V. L. Pushpavalli, Dr. Manika Pal-Bhadra

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 1.31 MB

english, 2012

21

Drosophila Argonaute-1is critical for transcriptional cosuppression and heterochromatin formation

Sreerangam N. C. V. L. Pushpavalli, Indira Bag, Manika Pal-Bhadra, Utpal Bhadra

Journal:

Chromosome Research

Année:

2012

Langue:

english

Fichier:

PDF, 1.40 MB

english, 2012

22

Synthesis and biological evaluation of 4β-sulphonamido and 4β-[(4′-sulphonamido)benzamide]podophyllotoxins as DNA topoisomerase-IIα and apoptosis inducing agents

Ahmed Kamal, Paidakula Suresh, M. Janaki Ramaiah, Adla Mallareddy, Syed Imthiajali, S.N.C.V.L. Pushpavalli, A. Lavanya, Manika Pal-Bhadra

Journal:

Bioorganic & Medicinal Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 1.32 MB

english, 2012

23

Synthesis, anticancer activity and apoptosis inducing ability of bisindole linked pyrrolo[2,1-c][1,4]benzodiazepine conjugates

Ahmed Kamal, Y.V.V. Srikanth, M. Janaki Ramaiah, M. Naseer Ahmed Khan, M. Kashi Reddy, Md. Ashraf, A. Lavanya, S.N.C.V.L. Pushpavalli, Manika Pal-Bhadra

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2012

Langue:

english

Fichier:

PDF, 1.31 MB

english, 2012

24

Synthesis and anticancer activity of chalcone-pyrrolobenzodiazepine conjugates linked via 1,2,3-triazole ring side-armed with alkane spacers

Ahmed Kamal, S. Prabhakar, M. Janaki Ramaiah, P. Venkat Reddy, Ch. Ratna Reddy, A. Mallareddy, Nagula Shankaraiah, T. Lakshmi Narayan Reddy, S.N.C.V.L. Pushpavalli, Manika Pal-Bhadra

Journal:

European Journal of Medicinal Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 824 KB

english, 2011

25

Synthesis and apoptosis inducing ability of new anilino substituted pyrimidine sulfonamides as potential anticancer agents

Ahmed Kamal, D. Dastagiri, M. Janaki Ramaiah, J. Surendranadha Reddy, E. Vijaya Bharathi, M. Kashi Reddy, M. Victor Prem Sagar, T. Lakshminarayan Reddy, S.N.C.V.L. Pushpavalli, Manika Pal-Bhadra

Journal:

European Journal of Medicinal Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 724 KB

english, 2011

26

Synthesis and biological evaluation of novel triazoles and isoxazoles linked 2-phenyl benzothiazole as potential anticancer agents

Ravindra M. Kumbhare, Umesh B. Kosurkar, M. Janaki Ramaiah, Tulshiram L. Dadmal, S.N.C.V.L. Pushpavalli, Manika Pal-Bhadra

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2012

Langue:

english

Fichier:

PDF, 383 KB

english, 2012

27

RNAi Components Are Required for Nuclear Clustering of Polycomb Group Response Elements

Charlotte Grimaud, Frédéric Bantignies, Manika Pal-Bhadra, Pallavi Ghana, Utpal Bhadra, Giacomo Cavalli

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 919 KB

english, 2006

28

Distinct methylation patterns in histone H3 at Lys-4 and Lys-9 correlate with up- & down-regulation of genes by ethanol in hepatocytes

Manika Pal-Bhadra, Utpal Bhadra, Daniel E. Jackson, Linga Mamatha, Pil-Hoon Park, Shivendra D. Shukla

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 1.09 MB

english, 2007

29

Cosuppression of Nonhomologous Transgenes in Drosophila Involves Mutually Related Endogenous Sequences

Manika Pal-Bhadra, Utpal Bhadra, James A. Birchler

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 553 KB

english, 1999

30

Cosuppression in Drosophila: Gene Silencing of Alcohol dehydrogenase by white-Adh Transgenes Is Polycomb Dependent

Manika Pal-Bhadra, Utpal Bhadra, James A Birchler

Journal:

Année:

1997

Langue:

english

Fichier:

PDF, 3.12 MB

english, 1997

31

RNAi Related Mechanisms Affect Both Transcriptional and Posttranscriptional Transgene Silencing in Drosophila

Manika Pal-Bhadra, Utpal Bhadra, James A Birchler

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 559 KB

english, 2002

32

Plant HDAC inhibitor chrysin arrest cell growth and inducep21WAF1by altering chromatin of STAT response element in A375 cells

Manika Pal-Bhadra, M Janaki Ramaiah, T Lakshminarayan Reddy, Anita Krishnan, SNCVL Pushpavalli, K Suresh Babu, Ashok K Tiwari, J Madhusudana Rao, Jhillu S Yadav, Utpal Bhadra

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 1.85 MB

english, 2012

33

Design, synthesis and biological evaluation of imidazo[1,5-a]pyridine–PBD conjugates as potential DNA-directed alkylating agents

Kamal, Ahmed, Ramakrishna, G., Ramaiah, M. Janaki, Viswanath, A., Rao, A. V. Subba, Bagul, Chandrakant, Mukhopadyay, Debasmitha, Pushpavalli, S. N. C. V. L., Pal-Bhadra, Manika

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 586 KB

english, 2013

34

Imidazo–benzothiazoles a potent microRNA modulator involved in cell proliferation

Pushpavalli, Sreerangam N.C.V.L., Janaki Ramaiah, M., Lavanya, A., Raksha Ganesh, A., Kumbhare, Ravindra M., Bhadra, Kaustav, Bhadra, Utpal, Pal-Bhadra, Manika

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2012

Langue:

english

Fichier:

PDF, 984 KB

english, 2012

35

Synthesis and study of benzothiazole conjugates in the control of cell proliferation by modulating Ras/MEK/ERK-dependent pathway in MCF-7 cells

Kamal, Ahmed, Faazil, Shaikh, Ramaiah, M. Janaki, Ashraf, Md., Balakrishna, M., Pushpavalli, S.N.C.V.L., Patel, Nibedita, Pal-Bhadra, Manika

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2013

Langue:

english

Fichier:

PDF, 1.43 MB

english, 2013

36

Quinazolino linked 4β-amidopodophyllotoxin conjugates regulate angiogenic pathway and control breast cancer cell proliferation

Kamal, Ahmed, Tamboli, Jaki R., Ramaiah, M. Janaki, Adil, S.F., Pushpavalli, S.N.C.V.L., Ganesh, Raksha, Sarma, Pranjal, Bhadra, Utpal, Pal-Bhadra, Manika

Journal:

Bioorganic & Medicinal Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 2.95 MB

english, 2013

37

Novel anthranilamide-pyrazolo[1,5-a]pyrimidine conjugates modulate the expression of p53-MYCN associated micro RNAs in neuroblastoma cells and cause cell cycle arrest and apoptosis

Ramaiah, M. Janaki, Pushpavalli, Sreerangam N.C.V.L., Lavanya, A., Bhadra, Kaustav, Haritha, V., Patel, Nibedita, Tamboli, Jaki R., Kamal, Ahmed, Bhadra, Utpal, Pal-Bhadra, Manika

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2013

Langue:

english

Fichier:

PDF, 2.08 MB

english, 2013

38

Cancer cell-selective promoter recognition accompanies antitumor effect by glucocorticoid receptor-targeted gold nanoparticle

Sau, Samaresh, Agarwalla, Pritha, Mukherjee, Sudip, Bag, Indira, Sreedhar, Bojja, Pal-Bhadra, Manika, Patra, Chitta Ranjan, Banerjee, Rajkumar

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 1.83 MB

english, 2014

39

A spatio-temporal cardiomyocyte targeted vector system for efficient delivery of therapeutic payloads to regress cardiac hypertrophy abating bystander effect

Rana, Santanu, Datta, Kaberi, Reddy, Teegala Lakshminarayan, Chatterjee, Emeli, Sen, Preeta, Pal-Bhadra, Manika, Bhadra, Utpal, Pramanik, Arindam, Pramanik, Panchanan, Chawla-Sarkar, Mamta, Sarkar, Sa

Journal:

Journal of Controlled Release

Année:

2015

Langue:

english

Fichier:

PDF, 4.91 MB

english, 2015

40

Interaction Map and Selection of microRNA Targets in Parkinson's Disease-Related Genes

Santosh P., Shinde, Arora, Neelima, Sarma, Pranjal, Pal-Bhadra, Manika, Bhadra, Utpal

Journal:

Journal of Biomedicine and Biotechnology

Année:

2009

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2009

41

Drosophila oncogene Gas41 is an RNA interference modulator that intersects heterochromatin and the small interfering RNA pathway

Gandhi, Sumit G., Bag, Indira, Sengupta, Saswati, Pal-Bhadra, Manika, Bhadra, Utpal

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 1.73 MB

english, 2015

42

DrosophilaMOF regulates DIAP1 and induces apoptosis in a JNK dependent pathway

Pushpavalli, Sreerangam N. C. V. L., Sarkar, Arpita, Ramaiah, M. Janaki, Koteswara Rao, G., Bag, Indira, Bhadra, Utpal, Pal-Bhadra, Manika

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 3.64 MB

english, 2016

43

Synthesis and mechanistic aspects of 2-anilinonicotinyl-pyrazolo[1,5-a]pyrimidine conjugates that regulate cell proliferation in MCF-7 cells via estrogen signaling

Kamal, Ahmed, Faazil, Shaikh, Hussaini, S.M. Ali, Ramaiah, M. Janaki, Balakrishna, M., Patel, Nibedita, Pushpavalli, S.N.C.V.L., Pal-Bhadra, Manika

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2016

Langue:

english

Fichier:

PDF, 1.34 MB

english, 2016

44

ChemInform Abstract: Synthesis and Biological Evaluation of Novel Triazoles and Isoxazoles Linked 2-Phenyl Benzothiazole as Potential Anticancer Agents.

Kumbhare, Ravindra M., Kosurkar, Umesh B., Ramaiah, M. Janaki, Dadmal, Tulshiram L., Pushpavalli, S. N. C. V. L., Pal-Bhadra, Manika

Journal:

Année:

2013

Fichier:

PDF, 26 KB

2013

45

ChemInform Abstract: Synthesis and Study of Benzothiazole Conjugates in the Control of Cell Proliferation by Modulating Ras/MEK/ERK-Dependent Pathway in MCF-7 Cells.

Kamal, Ahmed, Faazil, Shaikh, Ramaiah, M. Janaki, Ashraf, Md., Balakrishna, M., Pushpavalli, S. N. C. V. L., Patel, Nibedita, Pal-Bhadra, Manika

Journal:

Année:

2014

Fichier:

PDF, 25 KB

2014

46

The maleless gene mitigates global aneuploid effect and evolutionary shift from X to autosomes

Bhadra, Utpal, Gandhi, Sumit G., Palaparthi, Ramesh, Balyan, Manoj Kr., Pal-Bhadra, Manika

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2016

47

Evolution of circadian rhythms: from bacteria to human

Bhadra, Utpal, Thakkar, Nirav, Das, Paromita, Pal-Bhadra, Manika

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 2.05 MB

english, 2017

48

Cardinal Epigenetic Role of non-coding Regulatory RNAs in Circadian Rhythm

Bhadra, Utpal, Patra, Pradipta, Pal-Bhadra, Manika

Journal:

Molecular Neurobiology

Année:

2017

Langue:

english

Fichier:

PDF, 1.38 MB

english, 2017

49

Development and Biological Evaluation of Imidazothiazole propenones as Tubulin Inhibitors that Effectively Triggered Apoptotic Cell Death in Alveolar Lung Cancer Cell Line

Bin Sayeed, Ibrahim, Garikapati, Koteswara Rao, Makani, Venkata Krishna Kanth, Nagarajan, Apoorva, Shareef, Mohd Adil, Alarifi, Abd-Allah, Pal-Bhadra, Manika, Kamal, Ahmed

Journal:

ChemistrySelect

Année:

2017

Langue:

english

Fichier:

PDF, 7.46 MB

english, 2017

50

Epigenetic regulation of miR-200 as the potential strategy for the therapy against triple-negative breast cancer

Janaki Ramaiah, M., Naushad, Shaik Mohammad, Lavanya, P.O.N., Gayatri, A., Vaishnave, S., Pal-Bhadra, Manika

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 938 KB

english, 2017